8 Vaccines For Covid-19 Hacks You Need to Know

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What is a Vaccine ?

vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins.

What is Vaccination ?

Vaccination is a safe, simple, and effective way of protecting people against harmful diseases before they come into contact with them. 

Are there side effects from vaccines?

Like any medicine, vaccines can cause mild side effects, such as a low-grade fever, or pain or redness at the injection site. Mild reactions go away within a few days on their own.

4 Categories of vaccines in clinical trial

  1. Whole Virus
  2. Viral Vector
  3. Nucleic Acid ( RNA & DNA)
  4. Protein Subunit.

vaccines
vaccines

VACCINE DATA

Covaxin

CountryIndia
ManufacturerBharat Biotech
GenericBBV152
Drug ClassWhole-Virion Inactivated Vaccine
Efficacy81%

Ingredients :

COVAXIN includes the following ingredients: COVAXIN contains 6µg of whole-virion inactivated SARSCoV-2 antigen (Strain: NIV-2020-770), and the other inactive ingredients such as aluminum hydroxidegel (250 µg), TLR 7/8 agonist (imidazoquinolinone) 15 µg, 2-phenoxyethanol 2.5 mg, and phosphate buffer saline up to 0.5 ml. The vaccine (COVAXIN ) thus has been developed by using inactivated/killed virus along with the aforementioned chemicals

WHAT ARE THE RISKS OF BHARAT BIOTECH COVID-19 VACCINE (COVAXIN )?

Side effects that have been reported with the Bharat Biotech COVID-19 (COVAXIN ) include:
Injection site pain / Swelling / Redness / Itching
Headache
Fever
Malaise/body ache
Nausea
Vomiting
Rashes

Source: https://www.bharatbiotech.com/images/covaxin/covaxin-fact-sheet.pdf

CoviShield

CountryIndia
ManufacturerSerum Institute of India
GenericAZD1222
Drug ClassVaccine
Efficacy70%

Ingredients :

The COVISHIELD™ Vaccine includes the following ingredients:
L-Histidine, L-Histidine hydrochloride monohydrate, Magnesium chloride hexahydrate,
Polysorbate 80, Ethanol, Sucrose, Sodium chloride, Disodium edetate dihydrate (EDTA), Water for
injection.

WHATARE THE BENEFITS OF THE COVISHIELD™ VACCINE?

In ongoing clinical trials, the COVISHIELD™ Vaccine has been shown to prevent COVID-19 disease
following 2 doses given between 4 and 12 weeks apart. The duration of protection against COVID-19
disease is currently unknown.
You may get protective immune response 4 weeks after the second dose of COVISHIELD™ vaccine.

WHATARE THE RISKS OF THE COVISHIELD™ VACCINE?

Side effects that have been reported with (COVISHIELD) include:
Very Common (may affect more than 1 in 10 people)
tenderness, pain, warmth, redness, itching, swelling or bruising where the injection is given
generally feeling unwell • feeling tired (fatigue)
• chills or feeling feverishFever
• headache
• feeling sick (nausea)
• joint pain or muscle ache

Common (may affect up to 1 in 10 people)
• a lump at the injection site
• fever
• being sick (vomiting)
• flu-like symptoms, such as high temperature, sore throat, runny nose, cough and chills

Uncommon (may affect up to 1 in 100 people)
• feeling dizzy
• decreased appetite
• abdominal pain
• enlarged lymph nodes
• excessive sweating, itchy skin or rash

These may not be all the possible side effects of the COVISHIELD™ Vaccine. Serious and
unexpected side effects may occur. COVISHIELD™ Vaccine is still being studied in clinical trials

Source: https://www.seruminstitute.com/pdf/covishield_fact_sheet.pdf

Sputnik – v

CountryRussia
ManufacturerGamaleya National Research Centre of Epidemiology and Microbiology
GenericGam-COVID-Vac
Drug ClassViral Vector Vaccine
Efficacy91%
  • Sputnik V is the world’s first registered vaccine based on a well-studied human adenoviral vector-based platform.
  • Sputnik V or Gam-COVID-Vac works as a two-part vaccine. It includes two adenovirus vectors recombinant human adenovirus type 26 (rAd26-S) and recombinant human adenovirus type 5 (rAd5-S).

The Countries that have approved Sputnik – V:

The Russia Federation, China, Italy , Mexico , Republic of Turkey , Africa , Republic of Mauritius, Philippines, Serbia , Vietnam, Antigua and Barbuda, Austria, Mali, Panama , Egypt, India, Venezuela, Palestine , Pakistan, Nicaragua , Mauritius , Argentina , Nicaragua, Iran, Iraq, Paraguay, Lebanon , Republic of Seychelles, Ghana , Nepal , Honduras , Bangladesh , Bolivia , Albania , San Marino , Maldives , Ecuador

Moderna   

CountryUS
ManufacturerModerna
GenericmRNA-1273
Drug ClassmRNA vaccine
Efficacythe vaccine efficacy in this new analysis was 95.6% for 18 to <65 and 86.4% for participants ≥65 years of age.

Source: https://www.fda.gov/media/144434/download

What is mRNA ?

Messenger RNA, or mRNA, plays a fundamental role in human biology, transferring the instructions stored in DNA to make the proteins required in every living cell.

The vaccine is mainly manufactured at two plants in the US, though Moderna also has operations in Switzerland, with Lonza, and in Sweden with Recipharm.

Johnson & Johnson – COVID-19 Janssen

CountryUS
ManufacturerJanssen Pharmaceutical Companies of Johnson & Johnson
GenericAd26.COV2-S
Drug ClassViral Vector Vaccine
Efficacy 66 % globally, 72 % in the U.S.
Janssen Covid – 19

BioNTechPfizer

CountryGermany
ManufacturerBioNTech
GenericComirnaty
Drug ClassmRNA Vaccine
Efficacy 95% (source)
  • The BNT162b2 COVID-19 vaccine manufactured by Pfizer and BioNTech demonstrated 95% efficacy.
  • Efficacy was consistent across age, gender, race and ethnicity demographics; observed efficacy in adults over 65 years of age was over 94%
  • THE PFIZER-BIONTECH COVID-19 VACCINE fact sheet: https://www.fda.gov/media/144413/download

Sinovac / CoronaVac

CountryChina
ManufacturerSinovac
GenericSinovac COVID-19
Drug ClassVero Cell Inactivated Vaccine
Efficacy65%
  • Sinovac Biotech Ltd. CoronaVac COVID-19 Vaccine is based on an inactivated pathogen made by growing the whole virus in a lab and then killing it. Sinovac’s strategy contrasts with many other COVID-19 vaccine development efforts involving their vaccine candidates’ RNA.

Novavax

CountryUS
ManufacturerNovavax
GenericNVX-CoV2373
Drug ClassProtein-based Subunit Vaccine
Efficacy 89.3 %

Novavax COVID-19 vaccine (NVX-CoV2373) (Covovax) is a prefusion protein coronavirus vaccine candidate made using Novavax’s proprietary nanoparticle technology, Matrix-M, an adjuvant to enhance immune responses and stimulate high levels of neutralizing antibodies.

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